Thermo Fisher Scientific TFF2 Polyclonal Antibody
인체 TFF2 단백질을 인식하는 폴리클로날 항체로, 면역조직화학(IHC) 등 연구용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 완충액에 0.1% sodium azide를 포함합니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 11 amino acid peptide from internal region of human TFF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551612 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon (100%); Marmoset, Dog (91%); Monkey, Mouse, Nematode (82%).
Target Information
Trefoil peptides are protease-resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds forming the trefoil motif (P-domain).
SP (spasmolytic polypeptide), also known as Trefoil factor 2 (TFF2) precursor, inhibits gastrointestinal motility and gastric acid secretion. It may also act as a structural component of gastric mucus, stabilizing glycoproteins through interactions with carbohydrate side chains.
Downregulation of SP expression is associated with primary gastric cancer, and its progressive loss is likely involved in early stages of gastric carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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