Thermo Fisher Scientific GPR143 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 314-404 of human GPR143 (NP_000264.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR143,uniProtId:P51810-1,ncbiNodeId:9606,antigenRange:314-404,antigenLength:404,antigenImageFileName:PA5-120094_GPR143_P51810-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120094_GPR143_P51810-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.98 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913666

Product Specific Information

Positive test controls include: U-251MG, BT-474, SW480, Mouse liver, Mouse kidney, Rat kidney. The target is usually found in the following locations: Apical cell membrane, Golgi apparatus, Lysosome membrane, Melanosome membrane, Multi-pass membrane protein.

Immunogen sequence: TGCSLGFQSP RKEIQWESLT TSAAEGAHPS PLMPHENPAS GKVSQVGGQT SDEALSMLSE GSDASTIEIH TASESCNKNE GDPALPTHGD L

Target Information

Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.