Thermo Fisher Scientific OCIAD2 Polyclonal Antibody
Human OCIAD2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, PBS와 sodium azide 포함. 세포 부착 및 이동 연구용으로 적합.
- 카탈로그번호
- PA520835
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–1 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide from near the carboxy terminus of human OCIAD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153189 |
Product Specific Information
- Suggested positive control: A549 cell lysate
- Compatible blocking peptide: PEP-0949
Target Information
OCIAD2 was identified by its sequence similarity with OCIAD1, forming the OCIA domain family. OCIAD2 mRNA is expressed at higher levels in invasive adenocarcinoma mixed subtype with bronchioloalveolar carcinoma component (BAC) of the lung.
Loss of OCIAD2 expression correlates with lymphatic invasion, blood vessel invasion, and lymph node metastasis, suggesting a role in cell adhesion and migration prevention.
Although its function remains unclear, OCIAD2 expression is associated with favorable prognosis in adenocarcinoma with BAC component and may serve as a marker for tumors treatable by limited surgery.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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