Thermo Fisher Scientific NAPRT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 309-538 of human NAPRT1 (NP_6602023) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NAPRT1,uniProtId:Q6XQN6-1,ncbiNodeId:9606,antigenRange:309-538,antigenLength:538,antigenImageFileName:PA5-88160_NAPRT1_Q6XQN6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88160_NAPRT1_Q6XQN6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.73 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804702

Product Specific Information

Immunogen sequence: ELGYRAVGVR LDSGDLLQQA QEIRKVFRAA AAQFQVPWLE SVLIVVSNNI DEEALARLAQ EGSEVNVIGI GTSVVTCPQQ PSLGGVYKLV AVGGQPRMKL TEDPEKQTLP GSKAAFRLLG SDGSPLMDML QLAEEPVPQA GQELRVWPPG AQEPCTVRPA QVEPLLRLCL QQGQLCEPLP SLAESRALAQ LSLSRLSPEH RRLRSPAQYQ VVLSERLQAL VNSLCAGQSP; Positive Samples: HepG2, HT-29; Cellular Location: Cytoplasm, cytosol

Target Information

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.