Thermo Fisher Scientific NAPRT1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: ELGYRAVGVR LDSGDLLQQA QEIRKVFRAA AAQFQVPWLE SVLIVVSNNI DEEALARLAQ EGSEVNVIGI GTSVVTCPQQ PSLGGVYKLV AVGGQPRMKL TEDPEKQTLP GSKAAFRLLG SDGSPLMDML QLAEEPVPQA GQELRVWPPG AQEPCTVRPA QVEPLLRLCL QQGQLCEPLP SLAESRALAQ LSLSRLSPEH RRLRSPAQYQ VVLSERLQAL VNSLCAGQSP
• Positive Samples: HepG2, HT-29
• Cellular Location: Cytoplasm, cytosol

Target Information

Nicotinic acid (NA; niacin)은 nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11)에 의해 NA mononucleotide (NaMN)로 전환되고, 이후 NA adenine dinucleotide (NaAD), 그리고 최종적으로 nicotinamide adenine dinucleotide (NAD)로 변환됩니다. NAD는 세포 내 산화환원 반응의 보조인자로 작용하며, 스트레스 반응을 포함한 다양한 세포 대사 과정에서 필수적인 역할을 합니다 (Hara et al., 2007).

⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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