Thermo Fisher Scientific Human ZSCAN4 Synthetic Peptide
인간 ZSCAN4 단백질의 C-말단 18개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20901의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며 PBS(pH 7.2)와 BSA, sodium azide 포함. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the carboxy terminus of human ZSCAN4.
PEP-1015 can be used as a blocking peptide with polyclonal antibody PA5-20901.
Target Information
Zygotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program, and the major burst of ZGA occurs only in the late 2-cell stage.
ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells.
Loss-of-function studies using siRNA show delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development.
ZSCAN4 plays an important role in preimplantation development and is involved in telomere maintenance and long-term genomic stability in ES cells, suggesting its critical importance in maintaining pluripotency in replicating stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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