Thermo Fisher Scientific Human LZTR2 Synthetic Peptide
인간 LZTR2 단백질의 C-말단 18개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20903의 차단 펩타이드로 사용 가능. PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the carboxy terminus of human LZTR2.
PEP-1017 can be used as a blocking peptide with polyclonal antibody PA5-20903.
Target Information
LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene.
LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation.
Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population, similar to that seen with the TMEM18, GNPDA2, BDNF, FAIM2, and MC4R genes in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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