Thermo Fisher Scientific Human TCF3 Synthetic Peptide
인간 TCF3의 N-말단 17개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 PA5-20900의 블로킹 펩타이드로 사용 가능. 액상 형태, PBS 버퍼 및 BSA 포함. 연구용으로만 사용되며 진단용 불가.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human TCF3.
PEP-1014 can be used as a blocking peptide with polyclonal antibody PA5-20900.
Target Information
TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, such as muscle or early B-cell differentiation.
Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) dimers bind DNA on E-box motifs: 5'-CANNTG-3'.
It binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases.
Two alternatively spliced human isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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