Thermo Fisher Scientific MRE11 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunoprecipitation (IP)

• Tested Dilution: 4–8 µL/mg of lysate

Product Specifications

Product Specific Information

• This product is preservative-free.
• It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
• This antibody has specificity for Human MRE11.

Target Information

MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex.
This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity, and meiosis.
The complex possesses single-stranded endonuclease activity and double-strand-specific 3′–5′ exonuclease activity provided by MRE11.
RAD50 is required to bind DNA ends and hold them in close proximity.
Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.