Thermo Fisher Scientific MRE11 Polyclonal Antibody
Human MRE11 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IP에 적합합니다. 보존제가 없는 액상 형태이며 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. DNA 이중가닥 절단 복구 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunoprecipitation (IP)
- Tested Dilution: 4–8 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the center region of Human MRE11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788096 |
Product Specific Information
- This product is preservative-free.
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human MRE11.
Target Information
MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex.
This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity, and meiosis.
The complex possesses single-stranded endonuclease activity and double-strand-specific 3′–5′ exonuclease activity provided by MRE11.
RAD50 is required to bind DNA ends and hold them in close proximity.
Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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