Thermo Fisher Scientific CCDC36 Monoclonal Antibody (OTI2F7), TrueMAB
인간 CCDC36 단백질을 인식하는 마우스 단클론 항체. Western blot에 적합하며, 1:2,000 희석 비율로 검증됨. 동결건조 형태로 제공되며, PBS 버퍼와 트레할로스를 포함. DNA 이중가닥 절단 형성 연구에 유용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F7 |
| Immunogen | Full length human recombinant protein of human CCDC36 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination.
Likely forms a complex with MEI4 and REC114 to activate DSB formation, an essential step for synapsis completion.
Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment, meiotic silencing of unsynapsed chromatin (MSUC), or meiotic surveillance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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