Thermo Fisher Scientific HPS1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human HPS1. Recombinant protein control fragment (Product #RP-101171). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HPS1,uniProtId:Q92902-1,ncbiNodeId:9606,antigenRange:374-458,antigenLength:700,antigenImageFileName:PA5-63938_HPS1_Q92902-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63938_HPS1_Q92902-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642536

Product Specific Information

Immunogen sequence: LWQGINLVLL TRSPSAPLAL VLSQLMDGFS MLEKKLKEGP EPGASLRSQP LVGDLRQRMD KFVKNRGAQE IQSTWLEFKA KAFSK

Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.

Target Information

Hermansky-Pudlak syndrome (HPS) is a rare, genetically heterogeneous, autosomal recessive disorder. It is characterized by oculocutaneous albinism, lysosomal storage defects and prolonged bleeding due to platelet storage pool deficiency. There are 10 HPS genes encoding HPS proteins that all interact within three distinct ubiquitously expressed protein complexes or biogenesis of lysosome-related organelle complexes. Defects in these genes cause HPS. HSP-1 is a component of multiple cytoplasmic organelles and is important for their normal development and function. It plays a role in intracellular protein sorting.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.