Thermo Fisher Scientific HPS1 Polyclonal Antibody
Thermo Fisher Scientific의 HPS1 Polyclonal Antibody는 인간 HPS1 단백질을 인식하는 토끼 IgG 항체로, 면역조직화학(IHC) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA563938
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HPS1. Recombinant protein control fragment (Product #RP-101171) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642536 |
Product Specific Information
- Immunogen sequence:
LWQGINLVLL TRSPSAPLAL VLSQLMDGFS MLEKKLKEGP EPGASLRSQP LVGDLRQRMD KFVKNRGAQE IQSTWLEFKA KAFSK - Highest antigen sequence identity to the following orthologs:
Mouse – 75%, Rat – 74%.
Target Information
Hermansky-Pudlak syndrome (HPS) is a rare, genetically heterogeneous, autosomal recessive disorder. It is characterized by oculocutaneous albinism, lysosomal storage defects, and prolonged bleeding due to platelet storage pool deficiency. There are 10 HPS genes encoding HPS proteins that all interact within three distinct ubiquitously expressed protein complexes or biogenesis of lysosome-related organelle complexes. Defects in these genes cause HPS. HSP-1 is a component of multiple cytoplasmic organelles and is important for their normal development and function. It plays a role in intracellular protein sorting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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