Thermo Fisher Scientific XRCC3 Monoclonal Antibody (10F1/6)
XRCC3 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단일클론 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 인간 XRCC3에 특이적입니다. 액상 형태로 제공되며 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:500 |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10F1/6 |
| Immunogen | His-tagged human XRCC3, over-expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_568779 |
Product Specific Information
- This antibody does not react with mouse samples.
- The target sequence has 100% sequence homology with non-human primate and 93% sequence homology with sheep, rat, and bovine.
- Suggested positive control: antigen standard for XRCC3 (transient overexpression lysate).
Target Information
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage.
It functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to various DNA-damaging agents and chromosomal instability.
A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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