Thermo Fisher Scientific UBA3 Polyclonal Antibody
UBA3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS buffer(40% glycerol)로 보관되며 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBA3. Recombinant protein control fragment (Product #RP-104232). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790406 |
Product Specific Information
Immunogen sequence:
YPPQVNFPMC TIASMPRLPE HCIEYVRMLQ WPKEQPFGEG VPLDGDDPEH IQWIFQKSLE RASQYNIRGV TYRLTQGVVK RIIPAVASTN AVIAAVCA
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1 (amyloid beta precursor protein binding protein) to form a heterodimer, and the enzyme complex activates NEDD8, a ubiquitin-like protein that regulates cell division, signaling, and embryogenesis.
Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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