Thermo Fisher Scientific CD154 (CD40 Ligand) Recombinant Armenian Hamster Monoclonal Antibody (MR1)
Armenian hamster 유래 재조합 단클론 항체로, 마우스 CD154(CD40 Ligand)을 특이적으로 인식합니다. Flow cytometry, 기능적 분석, 억제 분석 등에 사용 가능하며, Protein A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Functional Assay (Functional)
- Tested Dilution: Assay-dependent
Inhibition Assays (IA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Armenian hamster / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MR1 |
| Immunogen | This antibody was raised by immunising Armenian hamsters with murine activated Th1 (D1.6) plasma membrane. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
Product Specific Information
This antibody is specific for murine CD40 ligand (CD40L), a 39 kDa transmembrane glycoprotein. CD40L is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD40L interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.
Target Information
CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells, accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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