Thermo Fisher Scientific SCD Monoclonal Antibody (1B7)
SCD 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody(1B7). Western blot 및 ELISA에 적합하며 Human 시료에 반응. 비결합형 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B7 |
| Immunogen | SCD (NP_005054.3, 1–100 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MPAHLLQDDI SSSYTTTTTI TAPPSRVLQN GGDKLETMPL YLEDDIRPDI KDDIYDPTYK DKEGPSPKVE YVWRNIILMS LLHLGALYGI TLIPTCKFYT
Target Information
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, formed by desaturation of stearic acid. The stearic-to-oleic acid ratio influences cell growth and differentiation via effects on membrane fluidity and signal transduction.
Four SCD isoforms (Scd1–Scd4) exist in mouse, while humans have two isoforms (SCD1 and SCD5). SCD1 shares about 85% amino acid identity with all four mouse SCD isoforms and with rat Scd1 and Scd2. SCD5 shares limited homology with rodent SCDs and appears unique to primates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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