Thermo Fisher Scientific CD4 Monoclonal Antibody (S3.5), PerCP
인간 CD4 항원 인식용 마우스 모노클로날 항체로 PerCP 형광 표지되어 있으며, Flow Cytometry 분석에 적합합니다. 488 nm에서 여기되어 큰 Stokes shift를 가지며 R-PE 채널 간 간섭이 적습니다. 4°C 암소 보관, PBS/BSA/sucrose 완충액에 0.1% sodium azide 포함.
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Applications
- Flow Cytometry (Flow): Assay-Dependent
View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S3.5 |
| Immunogen | Human CD4 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with BSA, sucrose |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10374735 |
Additional Formats Available
- Unconjugated
- Alexa Fluor 405
- Alexa Fluor 488
- Alexa Fluor 700
- APC
- APC-Alexa Fluor 750
- APC-Cyanine5.5
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Alexa Fluor 610
- PE-Alexa Fluor 700
- PE-Cyanine5.5
- PE-Cyanine7
- PE-Texas Red
- Qdot 605
- Qdot 655
- Qdot 705
- Qdot 800
- TRI-COLOR
- Request custom conjugation
Product Specific Information
PerCP conjugates are excited by the 488 nm line of the argon-ion laser and have a large Stokes shift, providing minimal spectral overlap into the R-PE (phycoerythrin) channel.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is mainly expressed in T helper lymphocytes but can also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression occurs in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 contributes to early T-cell activation via association with the T-cell receptor complex and Lck kinase, and may mediate neuronal damage in immune-related CNS disorders.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
Analyte Specific Reagent
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