Thermo Fisher Scientific alpha Actinin 2 Monoclonal Antibody (GT1253)
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alpha Actinin 2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(파라핀) 실험에 적합합니다. 인간 및 마우스에 반응하며, Protein G로 정제된 액상 항체입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1253 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human alpha Actinin 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.27 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787167 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (94%), Pig (99%), Chicken (98%), Bovine (99%).
- Positive Control: HepG2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Alpha actinins belong to the spectrin gene superfamily, representing a diverse group of cytoskeletal proteins including alpha and beta spectrins and dystrophins.
Alpha actinin is an actin-binding protein with multiple roles in different cell types.
- In nonmuscle cells: localized along microfilament bundles and adherens-type junctions, binding actin to the membrane.
- In muscle cells (skeletal, cardiac, smooth): localized to the Z-disc and dense bodies, anchoring myofibrillar actin filaments.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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