Thermo Fisher Scientific Glutaminase C (GAC) Monoclonal Antibody (GT3211)
Glutaminase C 단백질을 검출하기 위한 Thermo Fisher Scientific의 Mouse monoclonal antibody. Western blot, IHC, ICC/IF에 적합하며 Human 및 Mouse 시료 반응성. 고순도 Protein G 정제, 1 mg/mL 농도, PBS buffer에 보존.
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Thermo Fisher Scientific Glutaminase C (GAC) Monoclonal Antibody (GT3211)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT3211 |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Glutaminase C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787166 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Bovine (100%).
- Positive Control: MCF-7, MDA-MB-231.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phosphate-activated glutaminase (EC 3.5.1.2) is the major enzyme yielding glutamate from glutamine. It has been demonstrated in human platelets (Sahai, 1983), and its significance is linked to behavioral disturbances where glutamate acts as a neurotransmitter (Prusiner, 1981). Studies by Sahai and Vogel (1983) indicated high heritability of platelet glutaminase with an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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