Thermo Fisher Scientific GluD2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human GLUD2 (NP_0362162) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GLUD2,uniProtId:P49448-1,ncbiNodeId:9606,antigenRange:319-558,antigenLength:558,antigenImageFileName:PA5-93088_GLUD2_P49448-1_Rabbit.svg,antigenImageFileNamePDP:PA5-93088_GLUD2_P49448-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.77 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806617

Product Specific Information

Immunogen sequence: YLHRFGAKCI AVGESDGSIW NPDGIDPKEL EDFKLQHGSI LGFPKAKPYE GSILEVDCDI LIPAATEKQL TKSNAPRVKA KIIAEGANGP TTPEADKIFL ERNILVIPDL YLNAGGVTVS YFEWLKNLNH VSYGRLTFKY ERDSNYHLLL SVQESLERKF GKHGGTIPIV PTAEFQDSIS GASEKDIVHS ALAYTMERSA RQIMHTAMKY NLGLDLRTAA YVNAIEKVFK VYSEAGVTFT; Positive Samples: A-549, MCF7, THP-1, A-431, Mouse brain, Mouse eye, Rat testis; Cellular Location: Mitochondrion matrix

Target Information

Glutamate dehydrogenase 2, Glud2, is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. Diseases associated with GLUD2 include Parkinson Disease, Late-Onset and Hyperinsulinemic Hypoglycemia, Familial, 6. Among its related pathways are GABA shunt and Carbon metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.