Thermo Fisher Scientific GluD2 Polyclonal Antibody
Thermo Fisher Scientific의 GluD2 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, IHC, ICC, ELISA에 적합합니다. 미토콘드리아 내 Glutamate Dehydrogenase 2 단백질을 검출하며, 고순도 Affinity Chromatography로 정제된 액상 항체입니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific GluD2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 319–558 of human GLUD2 (NP_0362162) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.77 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806617 |
Product Specific Information
Immunogen sequence:
YLHRFGAKCI AVGESDGSIW NPDGIDPKEL EDFKLQHGSI LGFPKAKPYE GSILEVDCDI LIPAATEKQL TKSNAPRVKA KIIAEGANGP TTPEADKIFL ERNILVIPDL YLNAGGVTVS YFEWLKNLNH VSYGRLTFKY ERDSNYHLLL SVQESLERKF GKHGGTIPIV PTAEFQDSIS GASEKDIVHS ALAYTMERSA RQIMHTAMKY NLGLDLRTAA YVNAIEKVFK VYSEAGVTFT
Positive Samples: A-549, MCF7, THP-1, A-431, Mouse brain, Mouse eye, Rat testis
Cellular Location: Mitochondrion matrix
Target Information
Glutamate dehydrogenase 2 (Glud2) is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate.
Diseases associated with GLUD2 include Parkinson Disease (Late-Onset) and Familial Hyperinsulinemic Hypoglycemia type 6. Related pathways include GABA shunt and Carbon metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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