Thermo Fisher Scientific LEFTY2 Monoclonal Antibody (1H6)
LEFTY2 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot 및 ELISA에 적합. 인간 시료 반응성. PBS 기반 액상형으로 보존제 무첨가. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H6 |
| Immunogen | LEFTY2 (NP_003231, 77–180 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
RFSQSFREVA GRFLASEAST HLLVFGMEQR LPPNSELVQA VLRLFQEPVP KAALHRHGRL SPRSAQARVT VEWLRVRDDG SNRTSLIDSR LVSVHESGWK AFDV
Target Information
Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis.
Lefty1 acts as a regulator of Lefty2 and NODAL, as the lack of the former results in bilateral expression of nodal, lefty2, and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness).
Lefty2 may play a role in endometrial bleeding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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