Thermo Fisher Scientific TGFB2 Polyclonal Antibody, MaxPab
TGFB2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 in situ PLA에 사용 가능. 인간 시료에 반응하며 PBS 기반 액상 형태로 제공. 고순도 친화 크로마토그래피 정제 제품으로 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
in situ PLA (PLA)
- Tested Dilution: 1:1200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TGFB2 (AAH99635.1, 1–414 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MHYCVLSAFL ILHLVTVALS LSTCSTLDMD QFMRKRIEAI RGQILSKLKL TSPPEDYPEP EEVPPEVISI YNSTRDLLQE KASRRAAACE RERSDEEYYA KEVYKIDMPP FFPSENAIPP TFYRPYFRIV RFDVSAMEKN ASNLVKAEFR VFRLQNPKAR VPEQRIELYQ ILKSKDLTSP TQRYIDSKVV KTRAEGEWLS FDVTDAVHEW LHHKDRNLGF KISLHCPCCT FVPSNNYIIP NKSEELEARF AGIDGTSTYT SGDQKTIKST RKKNSGKTPH LLLMLLPSYR LESQQTNRRK KRALDAAYCF RNVQDNCCLR PLYIDFKRDL GWKWIHEPKG YNANFCAGAC PYLWSSDTQH SRVLSLYNTI NPEASASPCC VSQDLEPLTI LYYIGKTPKI EQLSNMIVKS CKCS
Target Information
Transforming Growth Factor (TGF) betas mediate many cell-to-cell interactions during embryonic development. Three TGF betas (TGF beta 1, 2, and 3) are synthesized as precursor proteins, each cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.
TGF beta polypeptides influence cell proliferation, differentiation, and other functions across various cell types. Both transformed and nonneoplastic tissues release transforming growth factors, and nearly all mammalian cells possess a specific TGF receptor.
In general:
- Mesenchymal-origin cells are stimulated by TGF beta.
- Epithelial or neuroectodermal-origin cells are inhibited by TGF beta.
TGF beta 2 is produced by many cell types and found in high concentrations in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and ocular fluids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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