Thermo Fisher Scientific DREF Polyclonal Antibody
인간 DREF 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 1 mg/mL 농도의 액상 형태이며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 단기 보관, -20°C 장기 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 9–238 of Human DREF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545001 |
Product Specific Information
- Recommended positive controls: 293T, A431, Raji
- Predicted reactivity: Rhesus Monkey (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ZBED1, also known as DREF, is the human homolog of the Drosophila DREF protein, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation.
RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting a role in cell proliferation.
At least 22 ribosomal proteins possess ZBED1 binding sites in their promoters, and anti-ZBED1 RNAi decreased RP gene expression.
Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, required for nuclear localization and DNA binding.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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