Thermo Fisher Scientific EWSR Polyclonal Antibody
EWSR1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트에서 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the internal segment of EWSR1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Mouse brain tissue
- Cellular location: Nuclear
Target Information
This gene encodes a multifunctional protein involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport.
The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain.
Chromosomal translocations between this gene and transcription factor genes produce chimeric proteins implicated in tumorigenesis.
These chimeric proteins typically contain the N-terminal activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor.
Mutations, particularly translocations, are associated with Ewing sarcoma, neuroectodermal, and other tumors.
Alternative splicing results in multiple transcript variants, and related pseudogenes are found on chromosomes 1 and 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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