Thermo Fisher Scientific ECD/ SGT1 Monoclonal Antibody (PCRP-ECD-1D10)
Thermo Fisher Scientific의 ECD/SGT1 단클론 항체(PCRP-ECD-1D10)는 인간 ECD 단백질을 인식하는 Mouse IgG2b 형 항체로, ICC/IF, Flow Cytometry, IP 등에 사용 가능하며, 고순도 Protein A/G 정제 및 안정적인 PBS 기반 보존 용액을 제공합니다.
- 카탈로그번호
- 11319-MSM1-P0
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- pk
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Thermo Fisher Scientific ECD/SGT1 Monoclonal Antibody (PCRP-ECD-1D10)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Immunoprecipitation (IP) | 1–2 µg |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-ECD-1D10 |
| Immunogen | Recombinant full-length human ECD protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react with Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan, and Elephant (based on sequence homology).
Target Information
Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53, possibly by cooperating in part with TXNIP. May be involved in transcriptional regulation and has intrinsic transactivation activity enhanced by EP300. May act as a transcriptional activator required for glycolytic gene expression. Involved in regulation of cell cycle progression and may disrupt Rb-E2F binding, leading to transcriptional activation of E2F proteins. The cell cycle-regulating function may depend on RUVBL1-mediated association with the R2TP complex. May also play a role in regulation of pre-mRNA splicing. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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