
Thermo Fisher Scientific ECD/ SGT1 Monoclonal Antibody (PCRP-ECD-1D10)
ECD/SGT1 단클론 항체(PCRP-ECD-1D10)는 인간 ECD 단백질을 인식하며, ICC/IF, Flow Cytometry, IP, Peptide Array 등 다양한 응용에 적합합니다. Protein A/G로 정제된 액상 항체로, 1 mg/mL 농도이며 PBS(pH 7.4) 버퍼에 보존됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Immunoprecipitation (IP) | 1–2 µg |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-ECD-1D10 |
| Immunogen | Recombinant full-length human ECD protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Predicted to react with Rabbit, Goat, Horse, Guinea pig, Dog, Pig, Rhesus monkey, Orangutan, and Elephant (based on sequence homology).
Target Information
Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating with TXNIP. May be involved in transcriptional regulation and has intrinsic transactivation activity enhanced by EP300. Plays a role in the regulation of cell cycle progression and may disrupt Rb-E2F binding, leading to transcriptional activation of E2F proteins. The cell cycle-regulating function may depend on RUVBL1-mediated association with the R2TP complex. May also play a role in the regulation of pre-mRNA splicing. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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