Thermo Fisher Scientific Fibrillarin Recombinant Rabbit Monoclonal Antibody (ARC0506)
Thermo Fisher Scientific의 Fibrillarin Recombinant Rabbit Monoclonal Antibody (ARC0506)은 인간, 마우스, 랫트 시료에 반응하며 WB, ICC/IF, ELISA, IP에 적합합니다. HEK293 세포에서 발현된 재조합 단클론 항체로, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0506 |
| Immunogen | Synthetic peptide corresponding to amino acids 222–321 of human Fibrillarin/U3 RNP (P22087) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848966 |
Product Specific Information
Immunogen sequence:
KYRMLIAMVD VIFADVAQPD QTRIVALNAH TFLRNGGHFV ISIKANCIDS TASAEAVFAS EVKKMQQENM KPQEQLTLEP YERDHAVVVG VYRPPPKVKN
Target Information
Nop1p / Fibrillarin was originally identified as a nucleolar protein of baker’s yeast, Saccharomyces cerevisiae (accession P15646).
The Nop1p protein is essential for yeast viability and is localized in the nucleoli.
The human homologue of Nop1p is fibrillarin (accession P22087), a component of the nucleolar small nuclear ribonucleoprotein (snRNP) particle.
The human fibrillarin gene is located on chromosome 19 (19q13.1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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