
Thermo Fisher Scientific Human Precerebellin Synthetic Peptide
인간 Precerebellin 단백질의 C-말단 16개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 차단용으로 사용 가능하며, 인간 반응성 확인됨. 액상 형태, 고순도 정제, 연구용으로만 사용.
- 카탈로그번호
- PEP0278
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Precerebellin Synthetic Peptide
Thermo Fisher Scientific Human Precerebellin Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human Precerebellin.
PEP-0278 can be used as a blocking peptide with polyclonal antibody PA5-20159.
Target Information
Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka-dependent signaling pathway, and indirectly enhances adrenocortical secretion in vivo through a paracrine mechanism involving medullary catecholamine release.
The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells and cartwheel neurons of the dorsal cochlear nucleus.
Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin possesses additional functions beyond those already stated.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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