Thermo Fisher Scientific CD23 (Fc Epsilon RII) Monoclonal Antibody (FCER2/6888)
CD23(Fc Epsilon RII)에 특이적인 mouse monoclonal antibody로, 인간 시료에 반응합니다. IHC(P) 및 IHC(PFA) 실험에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. CD23 관련 B세포 연구 및 IgE 수용체 발현 분석에 적합합니다.
- 카탈로그번호
- 2208-MSM8-P1ABX
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FCER2/6888 |
| Immunogen | Recombinant fragment (around aa 48–321) of human FCER2/CD23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells, and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low-affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases of centroblastic/centrocytic lymphoma. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. A soluble form of CD23 acts as a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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