Thermo Fisher Scientific CD23 (Fc Epsilon RII) Recombinant Rabbit Monoclonal Antibody (FCER2/8509R)
인간 CD23(Fc Epsilon RII)을 인식하는 재조합 토끼 단클론 항체. IHC(P) 및 IHC(PFA) 실험에 적합하며, HEK293 세포에서 발현. Protein A/G로 정제된 액상 형태로 제공되며, 4°C 보관. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FCER2/8509R |
| Immunogen | Recombinant fragment (around aa 221–321) of human FCER2/CD23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD23 is a 45 kDa glycoprotein expressed on a subpopulation of peripheral blood and tonsil B cells, and is strongly expressed on EBV-transformed B lymphoblasts. It is identical to the low-affinity IgE receptor (Fc epsilon RII) found on B cells. CD23 expression has been observed in neoplastic cells from B cell chronic lymphocytic leukemia and some lymphomas. Functionally, CD23 is involved in B cell growth, differentiation, and IgE production, and also exists in a soluble form with mitogenic activity. CD23 dysfunction is associated with diseases such as chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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