Thermo Fisher Scientific CD23 (Fc Epsilon RII) Recombinant Rabbit Monoclonal Antibody (FCER2/8509R)
인간 CD23(Fc Epsilon RII)을 인식하는 재조합 토끼 단클론 항체로, IHC(P) 및 IHC(PFA)에 사용 가능. HEK293 세포에서 발현되며 Protein A/G로 정제됨. PBS(pH 7.4) 용액 형태, 방부제 없음, -20°C 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FCER2/8509R |
| Immunogen | Recombinant fragment (around aa 221–321) of human FCER2/CD23 protein (UniProt ID: P06734-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
CD23 is a 45 kDa glycoprotein expressed on a subpopulation of freshly isolated peripheral blood and tonsil B cells, and strongly expressed on EBV-transformed B lymphoblasts. It is identical to the low-affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some centroblastic/centrocytic lymphomas. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. A soluble form of CD23 acts as a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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