Thermo Fisher Scientific NUDT5 Recombinant Rabbit Monoclonal Antibody (7Y9M2)
NUDT5 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, ELISA에 사용 가능. 높은 특이성과 재현성을 제공하며, HEK293 발현 시스템에서 생산됨. 연구용으로 인간, 마우스, 랫트 시료에 반응.
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Thermo Fisher Scientific NUDT5 Recombinant Rabbit Monoclonal Antibody (7Y9M2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7Y9M2 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human NUDT5 (Q9UKK9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911751 |
Product Specific Information
Positive test controls include: HeLa, HepG2, A-431, Mouse thymus, Mouse liver, Rat kidney.
Immunogen sequence:
MESQEPTESS QNGKQYIISE ELISEGKWVK LEKTTYMDPT GKTRTWESVK RTTRKEQTAD GVAVIPVLQR TLHYECIVLV KQFRPPMGGY CIEFPAGLID
Target Information
NUDT5 is an enzyme that can act as an ADP-sugar pyrophosphatase or catalyze ATP synthesis in the presence of diphosphate.
In the absence of diphosphate, it hydrolyzes modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP, and 8-oxo-dGDP.
In the presence of diphosphate, it mediates nuclear ATP synthesis by converting ADP-ribose to ATP and ribose 5-phosphate.
Nuclear ATP generation is required for chromatin remodeling events.
NUDT5 does not play a role in U8 snoRNA decapping activity but binds U8 snoRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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