Thermo Fisher Scientific SNRPA1 Recombinant Rabbit Monoclonal Antibody (2D7M1)
SNRPA1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA에 적합. HEK293 발현 시스템에서 생산되었으며 0.8 mg/mL 농도로 제공. 인간, 생쥐, 랫드 반응성. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SNRPA1 Recombinant Rabbit Monoclonal Antibody (2D7M1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2D7M1 |
| Immunogen | Synthetic peptide corresponding to amino acids 156–255 of human SNRPA1 (UniProt ID: P09661) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911757 |
Product Specific Information
- Positive test controls: HepG2, RD, SH-SY5Y, Mouse liver, Mouse brain, Mouse pancreas
- Target localization: Nucleus
Immunogen sequence:
QEAEKMFKGK RGAQLAKDIA RRSKTFNPGA GLPTDKKKGG PSPGDVEAIK NAIANASTLA EVERLKGLLQ SGQIPGRERR SGPTDDGEEE MEEDTVTNGS
Target Information
SNRPA1 (U2 snRNP-A) is located on gene locus 15q26.3 and encodes a 28 kDa protein. It is a specific component of the U2 snRNP particle, containing a unique N-terminal leucine-rich region and a hydrophobic RNA-binding C-terminal region. Unlike other RNA-binding proteins, it lacks RNP1 and RNP2 motifs. SNRPA1 associates with U2 snRNP and plays roles in transcription and pre-mRNA splicing, potentially influencing cell division and proliferation. Autoantibodies against snRNP particles are often found in patients with connective tissue disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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