Thermo Fisher Scientific SNRPA1 Recombinant Rabbit Monoclonal Antibody (2D7M1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2D7M1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 156-255 of human SNRPA1 (P09661). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SNRPA1,uniProtId:P09661-1,ncbiNodeId:9606,antigenRange:156-255,antigenLength:255,antigenImageFileName:MA5-42616_SNRPA1_P09661-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42616_SNRPA1_P09661-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911757

Product Specific Information

Positive test controls include: HepG2, RD, SH-SY5Y, Mouse liver, Mouse brain, Mouse pancreas. The target is usually found in the following locations: Nucleus.

Immunogen sequence: QEAEKMFKGK RGAQLAKDIA RRSKTFNPGA GLPTDKKKGG PSPGDVEAIK NAIANASTLA EVERLKGLLQ SGQIPGRERR SGPTDDGEEE MEEDTVTNGS

Target Information

SNRPA1 (U2 snRNP-A) is located in gene map locus 15q26. 3 and is a 28 kDa protein, isa specific component of U2 snRNP particle and consists of a unique N-terminal leucine-rich region and an extremely hydrophobic RNA-binding C-terminal region. It lacks segments homologous to RNP1 and RNP2, commonA. A motifs found in several RNA-binding proteins. It associates with U2 snRNP and participates in transcription and pre-mRNA splicing. It might play an important role in cell division and proliferation. Patients with connective tissue disorders often produce autoantibodies against snRNP particles.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.