Thermo Fisher Scientific FAM120B Polyclonal Antibody
FAM120B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 2–8°C 보관 시 안정적입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide from near the carboxy terminus of human PGCC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152338 |
Product Specific Information
- Suggested positive control: rat thymus tissue lysate
- PA5-20801 can be used with blocking peptide PEP-0915.
Target Information
The transcription factor peroxisome proliferator-activated receptor gamma (PPARγ) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association with various co-factors.
One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promotes their differentiation into adipocytes, while knockdown of PGCC1 expression through RNA interference blocks this process.
PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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