Thermo Fisher Scientific TWA1 Polyclonal Antibody
Thermo Fisher Scientific의 TWA1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 Rabbit IgG 기반 항체입니다. Western blot과 IHC에 사용 가능하며 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 뇌 조직 lysate를 양성 대조군으로 권장합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the carboxy terminus of human TWA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153256 |
Product Specific Information
- A suggested positive control is human brain tissue lysate.
- PA5-20799 can be used with blocking peptide PEP-0913.
Target Information
TWA1 was identified through a two hybrid-associated protein screen with RanBPM.
TWA1 is well conserved through evolution and localized within the nucleus.
It interacts with RanBP9 and forms a protein complex with RanBPM and Muskelin.
TWA1 possesses the LisH-CTLH motif, found in proteins involved in microtubule dynamics, cell migration, nucleokinesis, and chromosome segregation.
These functions overlap with those suggested for the RanGTPase cycle.
Recent findings suggest an uncovered function of the RanGTPase cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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