Thermo Fisher Scientific Eotaxin 3 Polyclonal Antibody
Eotaxin-3(또는 CCL26)에 특이적인 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. WB 및 ELISA에 적합하며, 고순도의 Affinity Chromatography로 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24–94 of human CCL26 (NP_006063.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.03 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854900 |
Product Specific Information
Sequence of this protein is as follows:
TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQL
Target Information
Eotaxin-3 is a small cytokine belonging to the CC chemokine family, also known as CCL26 (Chemokine (C-C motif) ligand 26).
Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific cell types expressing their cognate receptors.
Eotaxin-3 is chemotactic for eosinophils and basophils and exerts its effects by binding to the chemokine receptor CCR3.
It is expressed by several tissues including heart, lung, and ovary, and in endothelial cells stimulated with interleukin 4.
The gene encoding this chemokine is located on human chromosome 7.
Eotaxin-3 induces migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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