
Thermo Fisher Scientific HIP1/Huntingtin-interacting Protein 1 Polyclonal Antibody
HIP1/Huntingtin-interacting Protein 1에 특이적인 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제. 인간 시료 반응성. 4°C 보관, 1년 안정성 보장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000–1:25,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 987 to 1037 of human Huntingtin-interacting protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Huntingtin disease is a neurodegenerative disorder caused by expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a proapoptotic, cargo-specific adaptor protein potentially involved in the pathogenesis of Huntingtin disease. HIP-1 may also play a role in clathrin coat recruitment to lipid membranes and tumorigenesis by supporting the survival of precancerous and cancerous cells. Its expression correlates with prostate and colon cancer metastasis, making it a possible prognostic factor for these cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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