Thermo Fisher Scientific EXOSC1 Monoclonal Antibody (OTI4B7), TrueMAB
EXOSC1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 IHC(P) 분석에 적합. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며 PBS 버퍼에 trehalose 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B7 |
| Immunogen | Full length human recombinant protein of human EXOSC1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
EXOSC1 is a core component of the mammalian exosome complex, essential for rapid degradation of AU-rich element-containing RNAs but not for poly(A) shortening. Its association with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing proteins 42 and 46.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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