Thermo Fisher Scientific C17orf37/XTP4 Polyclonal Antibody
C17orf37/XTP4 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 인간 및 설치류 등 여러 종에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 40–90 on human XTP4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The ERBB2 (neu/HER2) oncogene is a key predictor of patient outcomes and therapeutic response in breast cancer. C35 (C17orf37) is a novel tumor biomarker highly expressed in breast cancer. The C35 gene is located on chromosome 17q12, approximately 505 nucleotides from the 3′ end of the ERBB2 oncogene, which encodes the antigenic target for trastuzumab (Herceptin) therapy. The chromosomal arrangement of C35 and ERBB2 genes is tail-to-tail. The ORF37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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