Thermo Fisher Scientific PU.1 Polyclonal Antibody
Human PU.1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 등에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. THP-1 핵추출물로 검증되었고, Rat, Pig, Bovine에도 예측 반응성을 보임.
- 카탈로그번호
- PA527457
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–152 of Human PU.1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal, 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2544933 |
Product Specific Information
- Recommended positive control: THP-1 nuclear extract
- Predicted reactivity: Rat (81%), Pig (94%), Bovine (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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