Thermo Fisher Scientific PDGFD Monoclonal Antibody (OTI1C1), TrueMAB
인간 PDGFD 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 Flow cytometry에 적합. 고순도 친화 크로마토그래피 정제, 무보존제 제형. 연구용으로 종양 및 성장 인자 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–247 of human PDGFD produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The platelet-derived growth factor (PDGF) family includes PDGF-A, PDGF-B, PDGF-C, and PDGF-D. PDGF members form disulphide-bonded dimeric isoforms that regulate growth and survival in connective tissue cells.
PDGF-D, secreted as a disulphide-linked homodimer (PDGF-DD), promotes tumor growth by enhancing cell proliferation and neovascularization. It may contribute to brain and prostate cancer development. PDGF-D is expressed in fibroblastic adventitial cells, endothelial cells, and various tumor cell lines (ovarian, renal, lung, astrocytoma, medulloblastoma) and in the human kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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