Thermo Fisher Scientific CIDEA Polyclonal Antibody
Thermo Fisher Scientific의 CIDEA Polyclonal Antibody는 Mouse CIDEA 단백질을 인식하는 Rabbit IgG 항체로, WB, IHC, ICC/IF에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 µg/mL |
| Immunohistochemistry (IHC) | 2.5–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to amino acids 200–214 of mouse CIDE-A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152145 |
Product Specific Information
In Western blot applications, this antibody detects a band at approximately 25 kDa.
A suggested positive control is mouse heart tissue lysate.
PA5-19908 can be used with blocking peptide PEP-0034.
Target Information
This gene encodes the homolog of the mouse protein CIDEA that has been shown to activate apoptosis.
Apoptosis activation is inhibited by DNA fragmentation factor DFF45 but not by caspase inhibitors.
Mice lacking functional CIDEA show higher metabolic rates, increased lipolysis in brown adipose tissue, and elevated core body temperature under cold conditions.
These mice are resistant to diet-induced obesity and diabetes, suggesting a role for CIDEA in thermogenesis and lipolysis.
Alternatively spliced transcripts have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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