Thermo Fisher Scientific JAM-C Polyclonal Antibody
JAM-C 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체. Human 시료에 반응하며 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 260 and 310 of human Junctional Adhesion Molecule C (JAM3, UniProt ID: Q9BX67-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
JAM3 (Junctional Adhesion Molecule C) is involved in tight junction formation, contributing to cell-to-cell adhesion in epithelial and endothelial cell layers. It forms continuous seals around cells, serving as a barrier to solute and water passage through the paracellular space.
This protein is localized in tight junctions between high endothelial cells and, unlike other family members, does not adhere to leukocyte cell lines and forms only weak homotypic interactions. JAM3 acts as a receptor for other members of the junctional adhesion molecule family.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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