Thermo Fisher Scientific STIM2 Polyclonal Antibody
STIM2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, Lyophilized 형태로 제공. 인간, 마우스, 랫트 반응성. 연구용 한정 제품.
- 카탈로그번호
- ACC-064-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific STIM2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SAEKQWEVPDTASEC, corresponding to amino acid residues 583–597 of human STIM2 (Intracellular, C-terminus) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW), depending on sample size.
Ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
For long-term storage, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
In T lymphocytes, Ca²⁺ entry following antigen-receptor binding occurs through store-operated Ca²⁺ release-activated Ca²⁺ (CRAC) channels composed of ORAI1 and STIM1.
STIM1 acts as a Ca²⁺ sensor and activates CRAC channels by migrating to the plasma membrane from ER-like sites.
STIM2, a related molecule, inhibits STIM1-mediated Ca²⁺ entry and can form complexes with STIM1, suggesting a coordinated role in Ca²⁺ regulation.
At least three isoforms of STIM2 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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