Thermo Fisher Scientific PML Polyclonal Antibody
Human PML 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow Cytometry에 사용 가능. KLH-conjugated synthetic peptide를 면역원으로 제작. Protein A 및 항원 친화 크로마토그래피로 정제. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between 470–499 amino acids from human PML Sumoylation Site |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2284067 |
Target Information
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein interacts with and enhances the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition in base excision repair. It contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome and ubiquitin protein ligase E6AP, implying involvement in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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