Thermo Fisher Scientific ALKBH7 Polyclonal Antibody
ALKBH7 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilution
- Western Blot (WB): 1:200–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human ALKBH7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719949 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.
Target Information
ALKBH7 (alkB, alkylation repair homolog 7), also known as SPATA11, is a 221-amino acid protein belonging to the alkB family. ALKBH7 is one of several homologs of the Escherichia coli protein AlkB, which protects DNA and RNA from damage by reversing cytotoxic alkylation lesions such as 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) through oxidative demethylation. This reaction requires ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. The ALKBH7 gene is located on human chromosome 19, which spans over 63 million bases, contains approximately 1,400 genes, and is known for having the highest gene density among human chromosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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