Thermo Fisher Scientific Calreticulin (CALR) Monoclonal Antibody (OTI6H10)
Calreticulin 단백질을 표적하는 단일클론 항체로, Western blot에 최적화되어 있습니다. 인간, 생쥐, 랫트에 반응하며, IgG2a 아이소타입을 가진 Mouse 유래 항체입니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6H10 |
| Immunogen | Full length human recombinant protein of human CALR (NP_004334) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Calreticulin (Calr) is a calcium-binding chaperone that assists in protein folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) through the calreticulin/calnexin cycle.
It interacts transiently with monoglucosylated glycoproteins synthesized in the ER and with the DNA-binding domain of NR3C1, mediating its nuclear export.
Calreticulin may also regulate maternal gene expression and oocyte maturation via calcium homeostasis.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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