Thermo Fisher Scientific SERPINA3 Polyclonal Antibody
Thermo Fisher Scientific의 SERPINA3 Polyclonal Antibody는 인간 단백질에 반응하는 토끼 IgG 항체로, Western blot, IHC, ELISA에 적합합니다. Affinity Chromatography로 정제된 액상 형태이며, -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24–423 of human Alpha-1 Antichymotrypsin (SERPINA3) (NP_0010762) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.30 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804360 |
Product Specific Information
Immunogen sequence:
HPNSPLDEEN LTQENQDRGT HVDLGLASAN VDFAFSLYKQ LVLKAPDKNV IFSPLSISTA LAFLSLGAHN TTLTEILKGL KFNLTETSEA EIHQSFQHLL RTLNQSSDEL QLSMGNAMFV KEQLSLLDRF TEDAKRLYGS EAFATDFQDS AAAKKLINDY VKNGTRGKIT DLIKDLDSQT MMVLVNYIFF KAKWEMPFDP QDTHQSRFYL SKKKWVMVPM MSLHHLTIPY FRDEELSCTV VELKYTGNAS ALFILPDQDK MEEVEAMLLP ETLKRWRDSL EFREIGELYL PKFSISRDYN LNDILLQLGI EEAFTSKADL SGITGARNLA VSQVVHKAVL DVFEEGTEAS AATAVKITLL SALVETRTIV RFNRPFLMII VPTDTQNIFF MSKVTNPKQA
Positive Samples: Mouse testis, Mouse liver, Rat liver
Target Information
SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and serine protease inhibitor that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT is associated with amyloid plaques in Alzheimer’s disease and aged brain tissues. Regulation of serine proteases and their inhibitors is crucial in neuromuscular differentiation. Prostate-specific antigen (PSA), a chymotrypsin-like serine protease, predominantly complexes with Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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