Thermo Fisher Scientific LZK Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 500-759 of human MAP3K13 (NP_0012292461) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LZK,uniProtId:O43283-1,ncbiNodeId:9606,antigenRange:500-759,antigenLength:966,antigenImageFileName:PA5-87700_LZK_O43283-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87700_LZK_O43283-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804356

Product Specific Information

Immunogen sequence: CWRSSEPDKG QAGPWGCCQA DAYDPCLQCR PEQYGSLDIP SAEPVGRSPD LSKSPAHNPL LENAQSSEKT EENEFSGCRS ESSLGTSHLG TPPALPRKTR PLQKSGDDSS EEEEGEVDSE VEFPRRQRPH RCISSCQSYS TFSSENFSVS DGEEGNTSDH SNSPDELADK LEDRLAEKLD DLLSQTPEIP IDISSHSDGL SDKECAVRRV KTQMSLGKLC VEERGYENPM QFEESDCDSS DGECSDATVR TNKHYSSATW; Positive Samples: BxPC-3, U-87MG, LO2, BT-474, Mouse kidney, Mouse pancreas; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein

Target Information

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.