Thermo Fisher Scientific TPO (Thyroid Peroxidase) (Thyroid Marker) Monoclonal Antibody (TPO/3698)
인체 TPO 단백질을 표적으로 하는 단클론 항체로, 갑상선 표지자 연구에 적합합니다. IHC 및 Peptide Array 등 다양한 실험에 사용 가능하며, 고순도 Protein A/G 정제 제품입니다. PBS 버퍼에 보존제가 없는 액상 형태로 -20°C에서 보관합니다.
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- 7173-MSM8-P1ABX
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Thermo Fisher Scientific TPO (Thyroid Peroxidase) Monoclonal Antibody (TPO/3698)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TPO/3698 |
| Immunogen | Recombinant fragment of human TPO (around aa 685–804) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thyroid Peroxidase (TPO) is a membrane-bound glycoprotein enzyme essential for thyroid gland function. It catalyzes iodination of tyrosine residues in thyroglobulin and the coupling of iodotyrosines to produce thyroid hormones thyroxine (T4) and triiodothyronine (T3).
Mutations in the TPO gene can lead to thyroid-related disorders such as congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Several transcript variants exist, though some remain incompletely characterized.
Diseases associated with TPO include Thyroid Dyshormonogenesis 2A and Congenital Hypothyroidism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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