Thermo Fisher Scientific KIF3A Recombinant Rabbit Monoclonal Antibody (1C8K4)
KIF3A 단백질을 검출하기 위한 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 높은 특이성과 재현성을 제공하며, 인체·생쥐·랫드 반응성. 연구용으로만 사용 가능.
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Thermo Fisher Scientific KIF3A Recombinant Rabbit Monoclonal Antibody (1C8K4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1C8K4 |
| Immunogen | Synthetic peptide corresponding to amino acids 600–699 of human KIF3A (Q9Y496) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.15 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912026 |
Product Specific Information
- Positive test controls include: SH-SY5Y, Rat testis.
- Immunogen sequence:
YQEMIENYVH WNEDIGEWQL KCVAYTGNNM RKQTPVPDKK EKDPFEVDLS HVYLAYTEES LRQSLMKLER PRTSKGKARP KTGRRKRSAK PETVIDSLLQ
Target Information
Kinesins are a large family of microtubule-dependent motor proteins responsible for the distribution of organelles, vesicles, and macromolecular complexes throughout the cell. Members of the heterotrimeric kinesin II family, including KIF3A, B, and C, mediate anterograde transport of membrane-bound organelles in neurons and melanosomes, and facilitate transport between the endoplasmic reticulum and the Golgi apparatus. KIF3A also plays roles in neurogenesis and L-R axis determination during embryonic development. Loss of KIF3A function in mouse photoreceptors causes apoptotic cell death, indicating its essential role in kinesin II-mediated transport and proper cell fate determination.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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