Thermo Fisher Scientific CAD Recombinant Rabbit Monoclonal Antibody (0O8D6)
CAD 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF, ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. 안정적인 액상 형태로 제공되며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 0O8D6 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human CAD (P27708) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912024 |
Product Specific Information
- Positive test control: 293T cells
- Immunogen sequence:
MAALVLEDGS VLRGQPFGAA VSTAGEVVFQ TGMVGYPEAL TDPSYKAQIL VLTYPLIGNY GIPPDEMDEF GLCKWFESSG IHVAALVVGE CCPTPSHWSA
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cell proliferation.
This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis:
- Carbamoylphosphate synthetase (CPS II)
- Aspartate transcarbamoylase
- Dihydroorotase
This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, linking MAPK activation to de novo pyrimidine nucleotide biosynthesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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